Home Opioid Use Disorder Guideline (2023) 3.0 Evidence Review

3.3 Opioid Antagonist Treatment

3.3.i Oral Naltrexone

Naltrexone is an opioid receptor antagonist that blocks the euphoric effects of opioids at adequate doses.282 Potential benefits of naltrexone...

February 6th, 2025 38 views 0 likes
3.3.ii Extended-release Naltrexone

Extended-release naltrexone via monthly intramuscular injection may promote improved treatment adherence in comparison to oral naltrexone.282 Several randomized controlled trials...

February 6th, 2025 34 views 0 likes
3.3.iii Recommendations and Remarks for Opioid Antagonist Treatment

Based on the available evidence base for opioid antagonist treatment options, this guideline makes the following recommendations: Recommendation 8. Oral...

February 6th, 2025 32 views 0 likes